This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Related articles  • Similar articles in this journal  Topic Collections  • Thrombolysis  • Venous Thromboembolism  • Pain  • Cardiovascular System  • Rheumatology  • Osteoporosis  • Women's Health  • Women's Health, Other  • Vascular Malformations  • Drug Therapy  • Drug Therapy, Other  • Hematology/ Hematologic Malignancies  • Coagulation Disorders  • Alert me on articles by topic

A Multidisciplinary Therapeutic Approach

Pedro Redondo, MD

Arch Dermatol. 2008;144(7):922-926.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Venous malformations (VMs) are ectatic vessels that are morphologically and histologically similar to veins and have a low blood flow. The thin-walled vascular channels are composed of a deficient layer of smooth-muscle cells and are lined by quiescent endothelium. The TIE2 signaling pathway is critical for endothelial cell–smooth muscle cell communication in venous morphogenesis.¹ Venous malformations represent approximately one-half to two-thirds of all vascular malformations, and the majority of them are sporadic anomalies. The skin or mucosa that covers VMs varies in color according to the depth and degree of ectasia of the lesion. More superficial malformations are purple and deeper ones are blue, green, or even imperceptible. The lesions are soft to the touch, can have a nodular appearance, and empty with compression. Highly ectatic vessels sometimes contain small venous thromboses, producing pain and inflammation. Phleboliths, which are used as radiological markers of this type of . . . [Full Text of this Article]

DIAGNOSIS AND MUSCULOSKELETAL INVOLVEMENT


WHEN TO TREAT HEMOSTASIS AND LOCALIZED INTRAVASCULAR COAGULATION

ANGIOGENESIS: AN INTERMEDIATE STAGE BETWEEN THE HEMOSTATIC SYSTEM AND THE GROWTH OF VMs?

MULTIDISCIPLINARY APPROACH

AUTHOR INFORMATION

RELATED ARTICLES

Coagulation Disorders in Patients With Venous Malformation of the Limbs and Trunk: A Case Series of 118 Patients
Elisabeth Mazoyer, Odile Enjolras, Annouk Bisdorff, Jérome Perdu, Michel Wassef, and Ludovic Drouet
Arch Dermatol. 2008;144(7):861-867.
ABSTRACT | FULL TEXT  

Association of Localized Intravascular Coagulopathy With Venous Malformations
Anne Dompmartin, Aurélie Acher, Pascal Thibon, Sébastien Tourbach, Cédric Hermans, Véronique Deneys, Ben Pocock, Agnès Lequerrec, Daniel Labbé, Marie-Thérèse Barrellier, Romain Vanwijck, Miikka Vikkula, and Laurence M. Boon
Arch Dermatol. 2008;144(7):873-877.
ABSTRACT | FULL TEXT