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Excimer Laser as Adjuvant Therapy for Adult Cutaneous Langerhans Cell Histiocytosis
Curt A. Vogel, MPH, MD;
William Aughenbaugh, MD;
Harry Sharata, MD, PhD
Arch Dermatol. 2008;144(10):1287-1290.
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REPORT OF A CASE
An 86-year-old man with a history of chronic lymphocytic lymphoma presented for evaluation of a persistent erythematous, eroded eruption of the bilateral inguinal folds and gluteal cleft of 6 years' duration. The lesions were characterized by burning, stinging, and weeping. Previous treatments included systemic and topical antifungal agents, topical glucocorticoid preparations, topical immunomodulators, topical antibacterial agents, barrier creams, and various emollients, with minimal benefit. Previous biopsy findings were consistent with nonspecific spongiotic dermatitis. The results of TRUE Test (Thin-layer Rapid Use Epicutaneous Test; Allerderm Laboratories Inc, Phoenix, Arizona) allergen testing were negative. The patient denied bone pain, dyspnea, cough, abdominal pain, polydipsia, polyuria, urinary retention, fevers, chills, or weight loss. Physical examination revealed circumscribed erythematous plaques with superficial maceration and erosions involving the bilateral inguinal creases and lateral scrotum, with extension to the perineum and gluteal cleft. Erythematous . . . [Full Text of this Article]
THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
AUTHOR INFORMATION
Department of Dermatology, University of Wisconsin–Madison (Drs Vogel and Aughenbaugh), and Madison Skin & Research, Inc (Dr Sharata)
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