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Arch Dermatol. 2008;144(11):1509-1514.

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Diagnosis: Syringocystadenoma papilliferum (SP).

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Histologic examination of the lesion showed numerous villous papillary projections extending into the lumina of cystic invaginations, which were connected to a papillomatous epidermis. The epithelial lining consisted of a double-layered epithelium with an inner layer of tall columnar cells and an outer layer of small cuboidal cells. Histopathologic findings indicated a diagnosis of SP. There was no evidence of an epidermal nevus or any malignant changes. Complete excision of the lesion was performed, and after 6 months follow-up no recurrence was observed.

DISCUSSION

A rare and circumscribed hamartomatous malformation of apocrine and eccrine sweat glands, SP manifests a characteristic histopathologic appearance.¹ Pinkus² and Helwig and Hackney³ have given detailed accounts of this entity in their large published case series. It usually appears at birth or in early childhood, most frequently on the head and neck. In approximately 25% of cases, it is observed on other locations such as the trunk . . . [Full Text of this Article]

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Arch Dermatol. 2008;144(11):1509-1514.
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